The growth hormone has the modulating influence on the TsNS some functions, it is not only endocrine hormone, but also media even protein which takes part in work of TsNS. High concentration of an insulinopodobny growth factor and Somatotropinum (by the principle of work of negative feedback).
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A large number in a blood plasma of free fatty acids. Secretion of a growth hormone is suppressed for the account: Increase in secretion of hormones of androgens in the teenage period. The set of factors exerts impact on production of a growth hormone, somatoliberin and somatostatin. They are synthesized by neurosecretory cells in portal veins of a hypophysis, exerting direct impact on somatotropa. Peptide hormones of a hypothalamus, namely somatoliberin and somatostatin are the main regulators of development of Somatotropinum. The most part of the growth hormone circulating in blood it is connected by transport proteins of growth. In several hours after backfilling the maximum concentration is noted.Ĭoncentration of hormone at the healthy person makes about 1-5 ng/ml, and during peaks it can rise to 20 and even 45 units. Within 24 hours several peaks are observed, each of which comes in 3-5 hours. At elderly people it is minimum, as well as amplitude and frequency of peaks of secretion.įor days Somatotropinum level also changes. With age secretion begins to decrease gradually. This indicator approximately by 100 times exceeds hormone level at the adult. The highest level of this hormone is observed during pre-natal development – on 4 – 6 month of development. At the expense of a growth factor there is a stimulation of growth of the majority of internals. Many effects are provided with directly hormone, and some – at the expense of an insulinopodobny growth factor which development happens in a liver under the influence of a growth hormone. Also other effects of Somatotropinum are described: absorption strengthening by a bone tissue of calcium, the immunostimulating effect, etc. 
Besides, this hormone is important for regulation of carbohydrate metabolism due to increase of level of glucose. Also the growth hormone makes strong anticatabolic and anabolic impact, promotes combustion of fat and decrease in amount of subcutaneous fat, brakes an albuminolysis and strengthens its synthesis. This hormone is called a growth hormone for the reason that in teenagers and young people it causes acceleration of linear growth due to growth of tubular bones of extremities. It treats polypeptide hormones, to among which also placental lactogen and prolactin.
Somatotropinum (growth hormone) represents one of the hormones produced in a hypophysis share lobby.
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